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First-degree relatives of vitiligo patients have a 68% risk of developing the disease, and the concordance rate between monozygotic twins is approximately 23%.28,34 Five genome-wide association studies (GWAS) have been conducted on vitiligo in European and Asian populations, identifying at least 54 vitiligo susceptibility loci.49,50 Human leukocyte antigen region Several genes within the human leukocyte antigen (HLA) region, specifically in class I and II regions, are associated with vitiligo

In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, editors

This entails making autoantibodies, which keep the body constantly inflamed

A health article warned that there is no evidence that highdose vitamin C injections promote weight loss or skin whitening, and that they should be reserved for treating deficiencies or as part of cancer care

Hansen et al., 2013

However, the overall results depend on the consistency of treatment and maintaining healthy lifestyle habits